Detalhe da pesquisa
1.
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Cell
; 175(5): 1289-1306.e20, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30454647
2.
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nat Immunol
; 20(4): 458-470, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890796
3.
Leptin and insulin act on POMC neurons to promote the browning of white fat.
Cell
; 160(1-2): 88-104, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25594176
4.
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Nat Immunol
; 16(11): 1153-61, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437244
5.
Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.
Immunity
; 45(4): 749-760, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27717799
6.
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
EMBO J
; 39(2): e103637, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31803974
7.
Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy.
Angew Chem Int Ed Engl
; 62(22): e202303818, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36973833
8.
Correction to: Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.
Diabetologia
; 67(1): 215, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37861718
9.
Early CCR6 expression on B cells modulates germinal centre kinetics and efficient antibody responses.
Immunol Cell Biol
; 95(1): 33-41, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27465674
10.
PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity.
J Autoimmun
; 76: 85-100, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27658548
11.
Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice.
Diabetologia
; 59(12): 2632-2644, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27628106
12.
Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.
Diabetologia
; 58(1): 122-31, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25338551
13.
PTPN2 restrains CD8⺠T cell responses after antigen cross-presentation for the maintenance of peripheral tolerance in mice.
J Autoimmun
; 53: 105-14, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997008
14.
Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis.
Cell Commun Signal
; 12: 13, 2014 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24606867
15.
CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse.
Immunol Cell Biol
; 91(5): 335-9, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23588497
16.
Stepwise progression of ß-selection during T cell development involves histone deacetylation.
Life Sci Alliance
; 6(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36283704
17.
Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity.
J Clin Invest
; 134(3)2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38060313
18.
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
bioRxiv
; 2023 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37397992
19.
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Nat Commun
; 14(1): 4524, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37500611
20.
PTPN2: a tumor suppressor you want deleted?
Immunol Cell Biol
; 95(10): 859-861, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28994418